Tuesday, July 24, 2007

 





The heart is an organ responsible for pumping the blood in the body. Through the blood, nutrients are provided to the body's cells and waste products are removed from these cells. The heart has four chambers: two upper chambers which are called atria and two lower chambers which are called ventricles. These chambers are also classified as left and right atrium and left and right ventricle, and each of them has a specific function.


The heart pumps the blood by repeated contractions of its muscles. These cardiac contractions are produced due to an electrical phenomenon called depolarization, that takes place in the heart muscles' cells (myocardial cells). The myocardial cells have a negative electric resting potential. Through the depolarization, this potential goes temporarily to a positive value that stimulates them to contract. Each heart cycle consists of two phases: depolarization, which represents the myocardial stimulation and repolarization, which represents the recovery phase. Both depolarization and repolarization are electrical phenomena.


Specialized conductive fibers inside the myocardium allow the transmission of cardiac stimulus to all the myocardial cells in a specific order. The atria contract first, and then the ventricles. Under normal conditions, the cardiac stimulus originates in a point, called sinoatrial node or sinus node, located in the posterior wall of the right atrium. The property of the node's cells to fire automaticaly and periodically an electric stimulus is called automaticity. However, the automaticity is a property posessed by all myocardial cells. In case the sinoatrial node fails to fire a stimulus, other myocardial cells will initiate this stimulation automatically.




wave produces a current wave of atrial contraction, which is called the P wave, as presented in the following figure. After a puse of about 1/10 of a second, the atrial depolarization wave reaches the atrioventricular node, which is situated between the two sets of chambers. The electrical stimulus passes then from the atrioventricular node through the bundle of His to the atrioventricular bundle branches, and the Purkinje fibers, which initiate the ventricular depolarization.
The ventricular depolarization is represented graphically on the electrocardiogram by an abrupt waveform called QRS complex, as presented in the following figure. During the ventricular depolarization, the right and


left ventricles contracts and pump the blood they contain. The QRS complex consists of three distinctive waves: Q, R and S. After the QRS complex, there is a pause, called ST segment. During the ventricular repolarization, which is represented by the T wave, the heart cells regain the negative polarization.
The sinoatrial node stimulates the heart at a rate of 60-80 beats per minute. If the sinoatrial node fails to fire an impulse, other cells from atria can do that instead. If this does not happen, then the artioventricular node can fire impulses at a rate of about 40-60 times per minute. Further, if no excitation occurs from the previous sources, the ventricular cells can fire a depolarization at a rate of about 20-40 times per minute.







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